General Cell Based Assays
Meso Scale Discovery U-PLEX Mouse IL-2 ASY
The Meso Scale Discovery U-PLEX Mouse IL-2 Assay Kit is a sensitive immunoassay for detecting and quantifying mouse interleukin 2 (IL-2) in various biological fluids It uses MSD s electrochemiluminescent technology and includes plates with capture antibodies detection antibodies calibrators and buffers for 96 tests With a sensitivity of 0 06 pg/mL and a range of 0 06-1500 pg/mL it requires only 25 L of sample and provides results in 3 5 hours Ideal for mouse vaccine studies immunotherapy research and cytokine profiling
Eurofins Discoverx PathHunter eXpress CXCR1 (IL8RA) U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0226E3CP0M)
The PathHunter CXCR1 (IL8RA) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL8/IL8) based activation of CXCR1 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CXCR1 and EA-tagged β-Arrestin-2. Activation of CXCR1 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical NFAT InhIbItr 10mg
A peptide inhibitor of NFAT; binds to the NFAT recognition site on calcineurin (IC50 = 25 pM) but does not inhibit calcineurin phosphatase activity at 100 µM; inhibits the dephosphorylation of NFAT in HEK293T lysates expressing NFAT1, -2, or -4; inhibits NFAT activation in RAW 264.7 macrophages, EA.hy926 endothelial cells, and isolated mouse thoracic aorta VSMCs (IC50s = 29.1, 30.2, and 45.7 µM, respectively, in reporter assays)
Eurofins Discoverx PathHunter Human IFN beta (IFNAR1/IFNAR2) Dimerization Cell-Based Assay Kit (HEK 293)
The PathHunter Human IFN beta (IFNAR1/IFNAR2) Stable Cell Line Dimerization Assay (HEK 293) measures ligand-induced dimerization of IFNAR1/IFNAR2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter Human PROKR2 β-Arrestin Cell-Based Assay Kit (CHO-K1)
The PathHunter Human PROKR2 β-Arrestin Stable Cell Line Assay (CHO-K1) contains a stable clonal cell line used to measure PROKR2 (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress P2RY11 CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0281E2CP2M)
The PathHunter P2RY11 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ATP) based activation of P2RY11 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged P2RY11 and EA-tagged β-Arrestin-2. Activation of P2RY11 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cayman Chemical 8-pCPT NAD sodIum salt 800ug
A derivative of NAD+; has been used in the screening of analog-sensitive PARP1 gatekeeper mutations
Abcam B-GLUCURONIDASE ACTIVITY ASSAY ..
B-GLUCURONIDASE ACTIVITY ASSAY ..
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter Human p53 (TP53) Nuclear Translocation Cell-Based Assay Kit (U2OS)
The PathHunter Human p53 (TP53) Stable Cell Line Nuclear Translocation Assay (U2OS) contains a stable clonal cell line used to measure p53 DNA damage pathway activation via nuclear translocation of p53. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress GPR3 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0626E2CP1L)
The PathHunter GPR3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR3 and EA-tagged β-Arrestin-2. Activation of GPR3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF pAb Anti-Mouse IgG Eu-Conjugate, 5,000 Assay Points
HTRF pAb Anti-Mouse IgG Eu-Conjugate, 5,000 Assay Points
Eurofins Discoverx PathHunter eXpress OSMR/IL6ST Dimerization Assay, 2pl Kit. (93-1056E3CP5M)
The PathHunter OSMR/IL6ST Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. oncostatin M) induced dimerization of OSMR/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside OSMR target protein fused to EA. Upon ligand-induced dimerization of OSMR/IL6ST, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress MC4R U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0211E3CP0M)
The PathHunter MC4R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. α-MSH) based activation of MC4R GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MC4R and EA-tagged β-Arrestin-2. Activation of MC4R stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress mCXCR2 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0513E2MCP0L)
The PathHunter mCXCR2 (IL8RB) eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CXCL8/IL-8) based activation of mCXCR2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged mCXCR2 and EA-tagged β-Arrestin-2. Activation of mCXCR2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.